Tmem63a

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August undefined, 2024

WebTmem63a transmembrane protein 63a MGI:2384789: Gene Ontology (GO) annotations for cytoskeleton All GO annotations for Tmem63a Filter annotations by: Aspect Category Evidence . Export: Text File Excel File . Gene Ontology Evidence Code Abbreviations: Experimental: EXP Inferred from experiment ... WebDec 8, 2024 · Summary. Enables mechanosensitive ion channel activity and osmolarity-sensing cation channel activity. Predicted to act upstream of or within ion transport. …

Tmem63a Mouse Gene Details transmembrane protein 63a

WebOct 21, 2015 · Contribute to syspremed/PanNETassigner development by creating an account on GitHub. A tag already exists with the provided branch name. Many Git commands accept both tag and branch names, so creating this branch may cause unexpected behavior. WebTMEM63A has 3,672 functional associations with biological entities spanning 8 categories (molecular profile, organism, chemical, functional term, phrase or reference, disease, phenotype or trait, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 58 datasets. the upper crust pies

TMEM63A CRISPR Knockout and Activation Products (m)

WebFurthermore, TMEM63A undergoes autophagy receptor TOLLIP-mediated autophagic degradation and is stabilized by VCP through blocking its lysosomal degradation. … WebAnti-TMEM63A antibody Description Rabbit polyclonal to TMEM63A Host species Rabbit Tested applications Suitable for: ICC/IF more details Species reactivity Reacts with: Human Predicted to work with: Mouse, Rat, Orangutan Immunogen Recombinant fragment corresponding to Human TMEM63A aa 200-350. Database link: O94886 Run BLAST with … WebGene "Gene description" Evidence A1CF "APOBEC1 complementation factor" "Evidence at protein level" A4GALT "Alpha 1,4-galactosyltransferase (P blood group)" "Evidence at protein le the upper crust pizza bishop ca

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WebNov 7, 2024 · While the physiological role of TMEM63A is incompletely understood, it is highly expressed in oligodendrocytes and it has recently been shown to be a MA ion channel. Using patch clamp electrophysiology, we demonstrated that each of the modeled variants result in strongly attenuated stretch-activated currents when expressed in naive cells. WebTMEM63A INFORMATION. Proteini. Full gene name according to HGNC. Transmembrane protein 63A. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. TMEM63A (KIAA0792) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). the upper crusts tvWebTMEM63A Antibody (PA5-69093) in WB. Western blot analysis of TMEM63A on human 293T cells. The sample was probed with a TMEM63A polyclonal antibody ( Product # PA5-69093) using a primary antibody dilution of 0.2-1.0 µg/mL. the upper crust pizzeria orrell

"WebTMEM63A, transmembrane protein 63A Vertebrate Orthologs 3 Human Diseases more Diseases 1 with human TMEM63A associations Mutations, Alleles, and Phenotypes less … " - Tmem63a

Tmem63a

WebTMEM63A CRISPR/Cas9 Knockout (KO) Plasmid (m) consists of a pool of three plasmids each encoding the Cas9 nuclease and a TMEM63A-specific 20 nt guide RNA (gRNA) designed for maximum knockout efficiency. gRNA sequences are derived from the GeCKO (v2) library and direct the Cas9 protein to induce a site-specific double strand break (DSB) … WebDec 8, 2024 · Tmem63a transmembrane protein 63a [ (house mouse)] Gene ID: 208795, updated on 8-Dec-2024 Summary Enables mechanosensitive ion channel activity and osmolarity-sensing cation channel activity. Predicted to act upstream of or within ion transport. Located in plasma membrane.

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WebNov 1, 2024 · OSCA/TMEM63 are an Evolutionarily Conserved Family of Mechanically Activated Ion Channels Mechanically activated (MA) ion channels convert physical forces … WebThe ELISA kits listed below target TMEM63A, the symbol for the human gene, transmembrane protein 63A, and a member of the CSC1 (TC 1.A.17) family. The protein encoded by TMEM63A has a predicted amino acid length of 807 and a mass of 92.1 kDa. TMEM63A may also be known by the following names: KIAA0792, and CSC1-like protein 1.

WebMar 30, 2024 · This observation suggests that TMEM63A should be added to the list of genes which can cause brain hypomyelination with spinal cord involvement beside DARS1 …

WebTMEM63A Antibody (PA5-66882) in ICC/IF. Immunofluorescent staining of TMEM63A in human cell line RT4 shows localization to microtubule organizing center and vesicles. … WebNov 1, 2024 · Our results suggest that OSCA/TMEM63 proteins are the largest family of MA ion channels identified, and are conserved across eukaryotes. Our findings will enable …

Transmembrane protein 63A is a protein that in humans is encoded by the TMEM63A gene. The mature human protein is approximately 92.1 kilodaltons (kDa), with a relatively high conservation of mass in orthologs. The protein contains eleven transmembrane domains and is inserted into the membrane of … See more Overview TMEM63A is located on the negative DNA strand of chromosome 1 at location 1q42.12, spanning base pairs 226,033,237 to 226,070,069. Aliases include KIAA0489 and KIAA0792. The … See more Properties and characteristics The mature form of the human TMEM63A protein has 807 amino acid residues with an isoelectric point of 6.925. This is fairly conserved across orthologs. A BLAST alignment revealed that the protein contains three … See more Paralogs TMEM63A has two paralogs: TMEM63B, which is located at 6p21.1, and TMEM63C, which is located at … See more • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G See more

WebJul 12, 2024 · TMEM63A is a newly-identified mechanosensitive ion channel. 75.6% ± 2.4% of Tmem63a + DRG neurons were IB4 + DRG neurons and 95.7% ± 1.7% of IB4 + DRG … the upper crust pizza north andoverWebThe ion channel construct is randomly integrated in the genome using lentiviral transduction. This cell line also expresses gene conferring Blasticidin resistance. These cells lines can … the upper crust queensWebMar 21, 2024 · TMEM63A (Transmembrane Protein 63A) is a Protein Coding gene. Diseases associated with TMEM63A include Leukodystrophy, Hypomyelinating, 19, Transient … the upper crust pizza saxonburg rdWebTMEM63A transmembrane protein 63A [ (human)] Gene ID: 9725, updated on 21-Mar-2024. Summary. Enables mechanosensitive ion channel activity. Predicted to be involved in … the upper crust sandwich shoppe riversideWebAnti TMEM63A pAb [Catalog No.: ATL-HPA068918] the upper cut hair salonWebMar 15, 2024 · 刘艾鑫，刘超 (1.延边大学医学院临床医学专业，吉林延吉 133000； 2.延边大学附属医院，吉林延吉 133000) Baló同心圆性硬化(BCS)，是一种罕见的而又具有特异性病理改变的中枢神经系统脱髓鞘疾病，是多发性硬化的一种亚型，其特征是明显的同心脱髓鞘模 … the upper cut crofton mdWebMay 5, 2024 · TMEM63B is enriched in the inner ear sensory hair cells. Genetic deletion of TMEM63B results in necroptosis of outer hair cells (OHCs) and progressive hearing loss. … the upper deck looss collection