Witryna2 dni temu · Orthologous to human IRGM (immunity related GTPase M). [provided by Alliance of Genome Resources, Apr 2024] Other designations. immunity-related GTPase family M protein 1, LPS-stimulated RAW 264.7 macrophage protein 47, immunity related GTPase m1, interferon-gamma-inducible GTPase Ifggd3 protein, … Immunity-related GTPase family M protein (IRGM), also known as interferon-inducible protein 1 (IFI1), is an enzyme that in humans is encoded by the IRGM gene. IRGM is a member of the interferon-inducible GTPase family. The encoded protein may play a role in the innate immune response by regulating … Zobacz więcej Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Zobacz więcej • Laukens D, Georges M, Libioulle C, Sandor C, Mni M, Vander Cruyssen B, et al. (November 2010). "Evidence for significant overlap between common risk variants for Crohn's disease and ankylosing spondylitis" Zobacz więcej
Irgm1 immunity-related GTPase family M member 1 [ (house …
Witryna17 sty 2013 · The understanding of the molecular pathways linked to the proviral or antiviral functions of autophagy is still at its beginning, especially regarding the molecular interplay between viruses and autophagy proteins. The human immunity-related GTPase family M (IRGM) protein was shown to be widely targeted by RNA viruses, … Witryna6 maj 2011 · Here, we examined a complete mouse 65-kilodalton (kD) guanylate-binding protein (Gbp) gene family as part of a 43-member IFN-γ–inducible guanosine triphosphatase (GTPase) superfamily in mouse and human genomes. Family-wide loss-of-function analysis found that at least four Gbps—Gbp1, Gbp6, Gbp7, and … how to save chrome profile
Extracellular Vesicles in the Arbuscular Mycorrhizal Symbiosis: …
Witryna13 kwi 2024 · Fujimoto, M. et al. CD19 regulates Src family protein tyrosine kinase activation in B lymphocytes through processive amplification. Immunity 13 , 47–57 (2000). Article CAS PubMed Google Scholar Witryna2 wrz 2011 · The immunity-related GTPases (IRGs) are a family of proteins induced by interferon-γ that play a crucial role in innate resistance to intracellular pathogens. The M subfamily of IRG proteins (IRGM) plays a profound role in this context, in part because of the ability of its members to regulate the localization and expression of … WitrynaThe prototypical DOCK protein, DOCK180, is an evolutionarily conserved Rac regulator and is indispensable during processes such as cell migration and myoblast fusion. The biological activity of DOCK180 is tightly linked to its binding partner ELMO. We previously reported that autoinhibited ELMO proteins regulate signaling from this pathway. how to save citrus seeds