WebDec 15, 2002 · Cisplatin and etoposide regimen is superior to cyclophosphamide, epirubicin, and vincristine regimen in small-cell lung cancer: results from a randomized phase III trial with 5 years' follow-up. S. Sundstrøm, R. Bremnes, +10 authors S. Aamdal Published 15 December 2002 Medicine WebCisplatin, 75 mg/ m2 IV, on day 1 is administered over 6 hours with normal saline and mannitol (7.5 g/l) at a rate of 125 ml/m2/hour. Vincristine, 1.5 mg/m2 (maximum, 2 mg), is given IV on days 1 and 8. Cyclophosphamide, 1,000 mg/m2 IV, is given over 1 …
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WebFeb 17, 2009 · The children received six to eight cycles of cisplatin (20 mg/m 2: days 1–5) and vincristine (1.4 mg/m 2: days 1, 8, 15), every 4 weeks. Objective response was … WebAnti-tumor mechanism of action of vincristine, paclitaxel, oxaliplatin and cisplatin leading to cell arrest and cell death. (A) Vincristine prevents microtubule aggregation, whereas paclitaxel prevents microtubule … reading assessment framework ks1
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WebJan 17, 2024 · Cisplatin/Etoposide (Category 1 with RT) 2-5,a. ... Shepherd FA, et al. Topotecan versus cyclophosphamide, doxorubicin, and vincristine for the treatment of recurrent small cell lung cancer. WebCisplatin and carboplatin can affect the kidneys. Giving plenty of fluids can help reduce this risk. These drugs can also affect hearing. Your child’s doctor may order hearing tests (audiograms) during or after treatment. Vincristine … WebThe major clinical use of vincristine is the treatment of acute lymphoblastic leukemia. It is used in combination therapy for Hodgkin's and non Hodgkin's lymphomas, sarcoma, breast cancer, small cell lung cancer, rhabdomyosarcoma, neuroblastoma, and Wilms' tumor. Pharmacokinetics how to stream your ps5 game to tiktok